How to Find and Replace Data in Excel with Python and Highlight Matches

Managing inconsistent data in Excel reports often requires manual edits, making verification difficult. Using Python with Spire.XLS for Python allows for automated find-and-replace operations that simultaneously highlight changed cells for visibility, supporting regular expressions and formula lookups. Additionally, Python automates the identification of duplicate and unique values, which is essential for cleaning merged registration forms or inventory lists. This replaces the repetitive interactive workflow of Excel's Conditional Formatting with a scalable, script-based approach for large datasets.