5 things to watch in 49ers’ preseason opener vs. Titans

The San Francisco 49ers face the Titans in their 2026 preseason opener at Levi’s Stadium, though over 20 players, including Christian McCaffrey, George Kittle, and Nick Bosa, are sidelined by injuries. Meanwhile, the Patriots report positive momentum ahead of their own preseason start. To bolster their roster before facing the Colts, the Patriots signed a veteran running back who previously played under Mike Vrabel during his tenure with the Tennessee Titans to add depth.